💊 Free GLP-1 Calculator

How GLP-1 Medications Work

GLP-1 (Glucagon-Like Peptide-1) medications are a class of drugs that help with weight loss by:

• Appetite suppression - Reduce hunger and cravings
• Slowed digestion - Feel full longer
• Blood sugar control - Improve insulin sensitivity
• Reduced food noise - Decrease obsessive thoughts about food

Clinical trials show 15-22% body weight loss over 72 weeks when combined with diet and exercise.

Popular GLP-1 Medications Compared

Medication	Active Ingredient	Monthly Cost	Avg Weight Loss
Ozempic	Semaglutide	$968	15%
Wegovy	Semaglutide	$1,349	15-22%
Mounjaro	Tirzepatide	$1,023	15-22%
Zepbound	Tirzepatide	$1,059	15-22%

Important Disclaimer

This calculator provides estimates only. Actual costs vary significantly based on:

• Insurance coverage and prior authorization
• Pharmacy benefits and copays
• Manufacturer discount programs (often 50%+ off)
• Compounding pharmacy options

Always consult with a healthcare provider before starting any medication. GLP-1 medications require a prescription and medical supervision.

Weight Loss Timeline Expectations

GLP-1 medications work progressively:

• Weeks 1-4: Initial adjustment, mild side effects, some appetite reduction
• Weeks 5-12: Steady weight loss begins, typically 5-10 lbs
• Weeks 12-24: Continued weight loss, often 10-15% total
• Months 6-12: Maintenance phase, goal weight achieved for many

GLP-1 vs Traditional Calorie Deficit

Both approaches create weight loss, but GLP-1 makes it significantly easier:

Factor	Calorie Deficit Alone	GLP-1 + Deficit
Weight Loss	1-2 lbs/week	1.5-3 lbs/week
Effort Required	High (hunger, willpower)	Lower (reduced appetite)
Side Effects	Usually none	Nausea, GI issues
Cost	Free	$1,000-1,350/month
Sustainability	Difficult long-term	Easier to maintain

Ways to Save on GLP-1 Medications

• Manufacturer coupons - Ozempic/Wegovy savings card can reduce to $0 with insurance
• Insurance negotiation - Appeal denials, check PBM pricing
• Compounding pharmacies - Often 40-60% cheaper (check legitimacy)
• Tirzepatide vs semaglutide - Similar results, different price points
• Discount programs - SingleCare, GoodRx can reduce costs

Frequently Asked Questions

How much do GLP-1 medications cost without insurance?

Without insurance or discounts, GLP-1 medications cost $1,000-$1,350/month. With manufacturer coupons, you may pay as little as $0-$25/month with commercial insurance.

Does insurance cover GLP-1 for weight loss?

Coverage varies widely. Medicare Part D covers some for obesity. Commercial insurance increasingly covers Wegovy and Zepbound, but prior authorization is often required.

What's the difference between Ozempic and Wegovy?

They contain the same ingredient (semaglutide) but are FDA-approved for different uses. Ozempic is for diabetes, Wegovy is specifically for weight loss and prescribed at higher doses.

Can I get compounded GLP-1?

Yes, but be cautious. Reputable compounding pharmacies can offer significant savings. Avoid "online clinics" with red flags - always verify pharmacy credentials with your state board of pharmacy.

How long do I need to take GLP-1 medication?

GLP-1 medications are typically long-term (1-2+ years) for weight loss maintenance. Most people regain weight if they stop medication without lifestyle changes.